DISCLAIMER: The information contained in this article is for general information and educational purposes only. It does not constitute medical advice. Therefore, any reliance you place on such information is strictly at your own risk. Please check with your medical doctor before starting or changing your CBD routine.

What is the Endocannabinoid system?

The Endocannabinoid System (ECS) is a recently discovered group of endogenous cannabinoid receptors found throughout the body. The endocannabinoid receptors that make up the ECS are located in our Central Nervous System (CNS), Peripheral Nervous System (PNS), and Immune System. Our CNS includes our brain and spinal cord, while the PNS acts as a communication network linking our CNS to the rest of our body.

Our brains contain the heaviest concentration of cannabinoid receptors, but there’s no shortage of them in our organs, tissues, glands, and more. The saturation of ECS receptors throughout our body is part of why CBD has so many uses and is so effective.

What is a Cannabinoid?

Cannabinoids are organic molecules naturally produced by hemp and cannabis which activate two of the body’s central nervous system receptors: CB1 and CB2.* CB1 receptors are primarily located in the brain, while CB2 receptors are spread throughout the rest of the body. Because CBD does not activate the brain’s CB1 receptors, it is largely non-psychoactive.

Each of the 100+ known cannabinoids has unique receptor interactions, producing individual results. Research has also shown that cannabinoids’ benefits multiply when used together, producing what is called the “entourage effect.” *More information on receptor activation and their effects on the body can be found on our blog, podcast or can be researched through reliable sources. We cannot provide health claims.

Where is Cannabidiol (CBD) found... in hemp?

Hemp contains at least 85 chemicals called cannabinoids. Cannabinoids are a class of diverse chemical compounds that act on cannabinoid receptors in cells that repress neurotransmitter release in the brain. Cannabidiol is one of those chemicals. It has been linked to pain relief and reduced inflammation as noted in this report from the National Cancer Institute.

How much CBD should I take?

A number of factors determine your ideal CBD serving. This can include your weight, metabolism, and genetics, among others. Because each individual’s endocannabinoid system is unique, some people may only require a small amount of CBD to receive their desired benefits, while others may require a much higher serving to experience the same effects.

If this is your first time trying CBD, we recommend starting with a small serving of only 10-25mg and increasing it later if desired. CBD can take time to work, so wait up to 2 hours before ingesting another serving. Some people may require up to 100-150mg per serving or more of CBD to get the desired effect. If you are concerned about your dosage or not getting the results you desire we suggest whether you are using our products or those of another you consult with Kassandra, Certified Cannabis Coach.

Is a standard hemp seed oil the same as a high CBD content CBD oil?

Absolutely not. Standard hemp oil, which can be found at a grocery store, and is a much different product than our Hemp CBD oil. Standard hemp oil is produced by cold pressing the seeds, whereas our CBD extract is from the hemp plant itself.

Is CBD from Hemp as good as CBD from marijuana?

The short answer is yes. CBD is CBD, whether from marijuana or hemp. Most marijuana has a very low cannabidiol profile, so most of the time hemp would be much more preferable regarding CBD potency because it naturally has such a high amount of it.

There are however certain strains of marijuana that are being grown with very high CBD content, but this is presently very rare. So, industrial hemp is not just an ideal alternative to marijuana but is most of the time the preferable choice.

What are the general benefits of CBD?

CBD is every bit as promising as it is versatile. It has been used in medical settings for countless reasons, from boosting the appetite of patients undergoing cancer treatments to treating epilepsy, Parkinson’s disease, diabetes, and other serious medical conditions.

It has also been used to treat a wide range of mental health problems, including addiction, seasonal affective disorder (SAD), post-traumatic stress disorder (PTSD) and anxiety.

If you are interested in learning everything there is to know about CBD—and how it can help you in your everyday life - head over to our blog.

Does CBD Get You High?

CBD is a product that does not contain THC, the psychoactive ingredient that makes all other cannabinoid products create a euphoric high. This allows for effective pain relief, anxiety treatment and more, all without potentially negative and unwanted psychiatric effects.

How Does CBD Work?

CBD works by connecting with a neurological network in our bodies that is called the “endocannabinoid system.” This system runs throughout your entire body and includes hundreds of thousands of receptors that can bind itself with cannabinoids you consume.

Depending on the specific cannabinoid we have consumed, the chemical reactions in our bodies will vary. As our endocannabinoid system is complex, cannabis can affect us in several ways, from altering our sleep schedule and appetite to treating a medical condition. This is what allows CBD to be such a powerful, effective, and versatile compound.

I have an anxiety disorder, will this help?

CBD can assist many, but I suggest speaking with your doctor. Its a broad statement, noting that anxiety breaks down into six categories: generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, specific phobias, and post-traumatic stress.

What are the common uses for CBD?

Common uses for CBD in medical settings:

  • Low doses of CBD is a medically approved treatment option for epilepsy
  • Evidence suggests that it could be an effective treatment for diabetes
  • Research shows that it can be used to manage symptoms of Parkinson’s disease
  • It is used as an appetite stimulant in different medical cases, including anorexia nervosa and nausea caused by undergoing cancer treatment
  • Despite naysayers who suggest the compound may be addictive, studies show that it can be used to combat cocaine and opioid addiction
  • There are product lines specifically created to address severe menstrual cramps Patients with multiple sclerosis (MS) use CBD to help manage symptoms and relieve pain
  • It can even have a positive impact on heart health

One of the primary benefits of using CBD as a pain reliever is the fact that unlike the more dangerous but popularly used drugs in the opioid family, CBD is not addictive. Many people who have real and serious struggles with chronic or acute pain will end up overdosing or developing long-term addictions to opioid painkillers but CBD offers a natural solution to this.

As it does not offer any recreational or “fun” benefits, the common uses of CBD products are focused on improving physical and mental health.

We are just beginning to conduct comprehensive, thorough research on the effects and benefits of CBD. However, it is already clear that CBD shows a lot of promise in providing an easy, non-addictive, non-psychoactive solution to a wide range of medical issues.

Will CBD relieve my pain?

CBD is a versatile treatment that can have a positive impact in patients battling a wide range of medical afflictions. While some of the product’s most promising effects benefit mental rather than physical health - it is a known fact that Cannabinoids directly have an interactive relationship with turning down the receptor system that ignites the feeling (message) of pain.

Common uses of CBD include serving as an alternative to highly addictive pain relievers and being used to curb existing substance addictions. That alone offers a boon to those in need. But that is just the tip of the iceberg when it comes to the effect CBD can have on a person’s mental health and wellbeing.

I’ve heard CBD can help with cognitive health and Alzheimer's?

Studies indicate that CBD may promote neurogenesis or, in easier terms to understand, the creation of new brain cells. As it has only been in recent years that scientists have learned that neurogenesis is even possible among fully-grown adults, this is yet another sign that CBD has the serious potential to improve mental health and wellness.

Are your products tested?

Beyond measure! In fact, we’ve gone beyond standards/practices through blockchain and Seed to Scale batch verification. All of our products are tested multiple times before and after the manufacturing process for potency and purity.

Is CBD Psychoactive?

CBD does not cause the mind-altering “high” that is often sought out amongst cannabis consumers. It’s another compound, tetrahydrocannabinol (THC), that causes the mind-altering effects. It is for this reason that CBD is not considered psychoactive. However, the compound does have an effect on the brain and your mood. CBD and THC both engage the brain in different ways. THC binds directly to special locations in the cell known as cannabinoid receptors.

When shopping how do I know the difference between CBD Extracts and Hemp seed Oil Extracts?

If you are trying CBD for the first time, you may not be sure what you should be searching for. For the first time buyer, it can be a challenge to sort through all of the options. Many retailers sell “hemp seed oil,” but these products should not be confused with CBD. Hemp seed oil, is extracted by pressing the seeds of the hemp plant. While hemp seed oil does possess a number of health-related benefits, hemp seeds do not contain any cannabinoids, so products labeled as “hemp seed oil” do not provide the reported benefits of CBD, or other cannabinoid-based products. The Hemp Industries Association makes the distinction between hemp seed oil and CBD extracts, stating, “CBD is not a product or component of hemp seeds and labeling to that effect is misleading and motivated by the desire to take advantage of the legal gray area of CBD under federal law. Hemp seed oil does not contain any significant quantity of CBD.

Are there heavy metals and pesticides in CBD products?

Hemp is a bioaccumulator, which means that it uptakes soil and air contents faster than it excretes them. This means that there is a potential for the CBD derived from hemp to retain environmental pollutants depending on where it is grown.  This can create serious problems from products derived from China or other places where there are large levels of soil contamination or air pollution. China is currently the world's largest hemp producer, and much of the CBD on the marketplace is produced overseas in places where there is less regulation regarding heavy metals. Even in the United States, there is potential for soil contamination on industrial lands, downstream of mines or other contaminated areas because hemp will accumulate toxins faster than other plants.

Hemp is a hearty plant, so pesticide usage on hemp itself is generally minimal. The problem is that hemp, being such a new crop, is often planted on land that was recently used for other agricultural purposes. Those previous crops are very likely to have been exposed to pesticides and the pesticides will stay in the soil for years. Hemp does an amazing job at removing and cleaning up the pesticides from the soil, but in this process will carry the pesticides into the plant and the finished product. Depending on where the hemp is grown, it may also be exposed to pesticides that are sprayed in the air. Since hemp is extracted and refined down, the pesticide levels reflected in finished products will generally be much higher than those found in other products grown in the same conditions.

Testing practices are critical to being able to ensure a safe and consistent product. We have all our CBD products third-party tested to make sure there are no heavy metals, pesticides, contaminants or impurities to ensure all our products are safe for consumption.

Do all your products contain Hemp oil or CBD? 

All are made with bioavailable activated cannabinoids - yes! Our CBD products are extracted from organic legal industrial hemp, which is grown to contain high concentrations of CBD. No hemp seeds are intentionally used during this process but may incidentally be extracted.

Is CBD Legal?

Yes. Hemp-derived CBD that contains less than 0.3% is legal in all 50 states and over 40 countries around the world. You do not need a prescription.

If I take CBD will I fail a drug test?

Evoq’s internal tincture products are THC FREE. Typical UA analysis tests are for THC and not CBD. While some of our products contain traces of THC (less than 0.3% THC), which is legal and very low, you could still possibly fail a drug test. If this is a concern, no worry, our CBD products contain ZERO THC. COA's (Certificate of Analysis) which are available for all third party tested products will show if the product contains zero THC or not.

Can I take too much CBD?

CBD is completely non-toxic. We have never heard of anyone ever overdosing on CBD. However, extremely large servings of CBD could cause drowsiness or loose stools based on carriers and purity of terpenes.

Are your products FDA approved?

The FDA recently approved a CBD-based drug called Epidiolex for the treatment of particular types of difficult-to-treat seizure disorders. CBD has not been approved by the FDA as a treatment for other conditions. However, studies are underway on CBD’s effects on a wide variety of conditions. Many ingredients within our products have been approved by the FDA for human consumption.


What are Terpenes? 

Evoq utilizes terpenes scientifically proven to enhance therapeutic effects and enhanced bioavailability. Terpenes are a class of volatile hydrocarbon compounds produced in the flower clusters of hemp and cannabis plants. Terpenes are naturally present in plants and they contribute to the plants’ unique taste, smell and color. Terpenes have been utilized by humans for millennia in a healing modality known as aromatherapy. Terpenes are recognized as safe for human consumption by the Food and Drug Association and are used in a wide variety of food and cosmetic products.

What are “diols?”

Diols and cannabinoids are used interchangeably and derived from cannabis. Example: Cannabidiols

  • Cannabidiol (CBD)
  • Cannabidiolic acid (CBDA)
  • Cannabidiorcol (CBD-C1)
  • Cannabidivarin (CBDV)
  • Cannabidivarinic acid (CBDVA)

In depth~ CBD is the most widely studied to impact our natural ECS system and have been shown to have a far greater influence on the body than ∆9-THC (tetrahydrocannabinol), and have the potential of affecting more than 1000 genes.

One attribute and examples is it up regulates gene expression of cellular antioxidant defenses through the pathway primary regulator of cellular antioxidant production, and down-regulating that of many inflammatory chemokines.

Reception of CB1 and CB2 influence the hippocampus and central nervous system (CNS), the immune system, and the peripheral nervous system.

CBD receptors are strongly stimulated by anandamide, whose name is taken from the Sanskrit word ananda, meaning joy or bliss.

CBD has been studied for immunomodulatory and may act as a neuroprotective antioxidant. Highly impactful, these studies demonstrate hope and resolve in effecting superior to alpha-tocopherol and ascorbate in preventing glutamate toxicity.

CBD has also been studied in settings of mood disorders, with effects possibly mediated by 5HT1A receptors. (reference 8) The innate immune system produces endogenous cannabinoids, and also expresses CBD receptors. (reference 5) In addition to NMDA and 5HT1A receptors, many other receptors have been shown to be affected by CBD including those which regulate calcium homeostasis and suppress tryptophan degradation.


Do THC and CBD get absorbed into the skin?

YES. Both THC and CBD are lipophilic, or fat-loving, with molecular weights below 400. That means these cannabinoids are absorbable through skin.

The skin’s cannabinoids affect all compartments of the skin by acting on various cell types and contribute to the skin’s healthy physiological function.

In depth, when activation of cannabinoid receptors (CB1 or CB2) are engaged, these functions of epidermal cells are modified – whether through proliferation, differentiation or apoptosis (cell death) – which are all important processes for the healthy physical defense of the body.

On Skin Conditions

CB2 receptors are very active in the skin. Symptoms of a malfunctioning endocannabinoid system can result in dermal issues like eczema and psoriasis. How’s it heal?

  1. CB2 helps replenish old skin cells, it heals damaged ones and throws out the dead ones. It also reduced inflammation, which is a prominent symptom of skin disease.
  2. CB2 receptors are underneath the epidermis, so by applying topical CBD, the pain receptors are dulled, which can help with painful conditions.

When absorbed into the skin, does it translate into the bloodstream?

YES, and NO, the amount absorbed depends on several factors, such as the type of topical ( cream or balm), combined ingredients in the topical, dermal thickness, and where it’s applied.

It’s important to seek out products that are free from synthetics and a lot of “fillers” that simply drives down price - and its benefits.

Can you get high from a topical containing THC, the psychoactive cannabinoid in cannabis?

It’s doubtful. You’d have to be swimming in it to feel the psychotropic effects of THC.

What’s the difference between topicals and patches?

The primary difference between topicals and patches is that topicals provide immediate release of the cannabinoid, while patches are designed for slow release over a period of time.

Patches are often used when individuals require continual delivery of the product, such as with chronic pain.

Just the Tips!

  1. An extra source of vitamins — We all know it’s hard to consume foods rich in all the nutrients our bodies need to be healthy. By adding CBD infused products to your skincare regime, you have one less thing to worry about knowing that your skin is getting all the Vitamins it needs to protect it from any sun damage and make sure it stays firm and tight for longer. It also has Vitamin A and D, which thanks to their regenerative qualities can undo years of dry and flaky skin.
  2. No more breakouts — Regularly applying hemp CBD oil to your skin provides it with healthy fatty acids, which are often found to be lacking in people with acne. Plus, it has antibacterial properties which treat infection (a major contributor to acne). But that’s not all! Fatty acids also protect and strengthen your skin’s outer layer resulting in fresher younger-looking skin.
  3. Fool your skin about your age — What if you could trick your cells into thinking they were 10 years younger? According to a study published in the Journal of Investigative Dermatology cannabinoid receptors in the brain, that form part of the endocannabinoid system, which interacts with CBD to increase our body’s natural ability to grow new skin cells. What does this all mean? CBD boosts your body’s regenerative process and actually encourages younger skin.
  4. Stop itching  — CBD has been linked to helping with conditions as severe as eczema. Instead of using cortisone for your next rash, consider the natural alternative of CBD which can battle dermatitis while hydrating your skin and eliminating dryness… Anyone who has experienced a New England winter knows how persistent and itchy dry skin can be!
  5. Moisture — hydration, hydration, hydration: the dermatologist’s mantra. Thanks to omega 3 and 6 fatty acids, cannabinoid oil is nature’s most effective moisturizer.
  6. If you have other skin conditions — although this is still pretty groundbreaking research, CBD oil has been used to help treat or help relieve symptoms from psoriasis, eczema, allergies, and even skin cancer, with successful results.


Here, you can really see how impactful CBD is on our endocrine system (skin). Take a SCROLL through this skin + cannabis experience!

Want to try it for yourself?

Give your skin a boost with a shot of our Organic Cannabidiol topical skin remedies.